Tomas Lindahl, Paul L. Modrich and Aziz Sancar were awarded the Nobel Prize in Chemistry on Wednesday for their studies of DNA repair.
Dr.
Lindahl, of the Francis Crick Institute in London, was honored for his
discoveries on base excision repair — the cellular mechanism that
repairs damaged DNA during the cell cycle. Dr. Modrich, of the Howard
Hughes Medical Institute in Chevy Chase, Md., and Duke University
Medical Center, was recognized for showing how cells correct errors that
occur when DNA is replicated during cell division. Dr. Sancar, of the
University of North Carolina, Chapel Hill, was cited for mapping the
mechanism cells use to repair ultraviolet damage to DNA.
They
shared the prize of 8 million Swedish kronor (around $960,000). The
prize was announced by Goran K. Hansson, permanent secretary of the Royal Swedish Academy of Sciences, which awarded the prize.
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